Outcomes of Amniotic Membrane Use as an Allograft in Flexor Tendon Repair

S. Shehata, Bejoal; M.A. Darwish, Abdou; Hassan, Khaled Mohamed; F. Hassan, Mohamed

doi:10.21608/mjmr.2024.298415.1731

Outcomes of Amniotic Membrane Use as an Allograft in Flexor Tendon Repair

Articles in Press

Document Type : Original Article

Authors

¹ Plastic and Reconstructive Surgery Department ,Faculty of Medicine , Minia University, Egypt

² Professor of Plastic Surgery, Faculty of Medicine, Minia University, Egypt

³ Professor of Plastic and Hand surgery, Plastic Surgery Department, Faculty of Medicine, Minia University, Egypt

⁴ Lecturer at Plastic Surgery Department, Faculty of Medicine, Minia University, Egypt

10.21608/mjmr.2024.298415.1731

Abstract

Introduction

Flexor tendon injuries of the hand are challenging problem for surgeons because of the following reasons.Firstly,such injuries cannot heal without surgical intervention.Secondly postoperative protocol should be done cautiously as mobilization was found to be crucial in preventing adhesions and improving gliding but there is a risk of rupture. Finally because the flexor tendons have unique anatomy within their sheaths.Many ideas were recently introduced to decrease the rate of adhesions, one of them is the use of Amniotic membrane (AM).

Aim of the work

The aim of this study is to evaluate using the amniotic membrane as an allograft around tendon repair site for prevention of peritendinous adhesions in cases of flexor tendon injuries in zones II,III of the hand in Minia University Hospital,Plastic&Reconstructive surgery department.

Patients and Methods

This is a prospective clinical study that was performed on 30 fingers at Minia University Hospital,Plastic Surgery department,with acute flexor tendon injury in zone II&III of the hand.

Results

The study included 30 fingers,males were 23 and 7 were females with age range 11-51 years.There was significant relation between application of the AM around tendon repair site and decreased rate of adhesions (P value < 0.05).Also there is improvement in the results range of motion.

Conclusion

In comparison with other techniques,the use of AM allograft seems to result in clinically meaningful improvement.This is proven from the results of our study.However,it is yet unknown if the undesirable results are related to technical issues,irregular distribution of complications or the amniotic membrane allograft itself.

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