The Prevalence of liver steatosis post liver transplantation

Moftah, Rofida Khalifa; Hassnine, Alshymaa Ahmed; Fathelbab, Hanaa Khalaf; Abdel Ghani, Wael

doi:10.21608/mjmr.2024.256206.1567

The Prevalence of liver steatosis post liver transplantation

Document Type : Original Article

Authors

¹ Tropical medicine department, faculty of medicine,Minia university ,Egypt

² Endemic medicine department,faculty of medicine,minia egypt

³ Endemic medicine department,faculty of medicine,Minia University, minia,Egypt

⁴ Endemic Medicine department, Faculty of Medicine, Minia University, Egypt

10.21608/mjmr.2024.256206.1567

Abstract

Introduction: After liver transplantation , non-alcoholic fatty liver disease (NAFLD) may develop as a recurrence or as de novo hepatic steatosis. It is unknown how the recurrence may affect the graft and patient outcomes. There is insufficient evidence to support its lack of effect on patient and graft survival.

Aim of the study: Identify prevalence of denovo or recurrent NAFLD in the post-transplant population

Materials& Methods: This is an observational cross sectional study ,during September 2021 to May 2023.This study included all recipients of living donor liver transplantation (LDLT) at Ain Shams center for Organ transplantation (ASCOT) , Ain shams university. All patients were conducted to detailed history, clinical examination, routine laboratory investigations in addition to abdominal ultrasonography. Transient elastography was done for positive US finding.

Results: we depended on imaging abdominal Ultrasonography and transient elastography and we found 36 patients among 150 patient visited outpatient transplant clinic within 18 month have steatosis. Seven of them (19%) underwent to LT because of NASH related cirrhosis and the rest of the patients ( 81%) have de novo steatosis.

Conclusion: liver transplant recipients have a significant risk of de novo or recurrent graft steatosis and fibrosis.

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