The effects of mycophenolate mofetil and mycophenolate sodium on kidney transplant recipients at the University Hospital for Nephrology and Urology in Minia, Egypt

Document Type : Original Article

Author

Internal Medicine and nephrology, Faculty of Medicine, Minia University

Abstract

Aim: The purpose of this research is to examine tacrolimus-based renal transplant patients and compare MMF with MPS..

Patients and Methods

Three hundred patients will be enrolled in this case-control research from Minia University Hospital's outpatient clinic.

There are two categories of subjects:

Group I: Fifty-five individuals undergoing a renal transplant on MPS

Group II: Fifty-five patients undergoing renal transplantation on MFF

Results: The p-value (<0.001) indicates that there is a statistically significant difference in BMI and dose between the two groups twice. The p value (<0.001) indicates that there is a statistically significant difference between the two groups in terms of S.Cr and a/c ratio.

In conclusion, there was no statistically significant difference in the safety or effectiveness of MMF and MPS. Compared to maintenance MMF dosages, MPS doses were greater. It is possible that immunosuppression will be improved with these greater dosages. There was no discernible difference in the two regimens' efficacies, nevertheless, according to our research. When deciding on a mycophenolic acid derivative, cost should be a major factor.

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Minia Journal of Medical Research

Articles in Press, Accepted Manuscript
Available Online from 25 February 2024

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