Effect of Dexmedotomin on spinal anesthesia in lower limb surgery.

Document Type : Original Article

Authors

1 Anesthesia and intensive care department,minia university,minia, Egypt

2 Anesthesiology and intensive care Department, Faculty of Medicine, Minia University.

3 anaethesia and intesive care department

Abstract

Background: Spinal anaesthesia is a commonly employed method for lower limb procedures due to its rapid onset, efficient sensory and motor blockage, and extended postoperative analgesic effects. Spinal anaesthesia offers a diverse range of local anaesthetic medications, including bupivacaine, levobupivacaine, and ropivacaine. The primary physical characteristic that significantly influences the degree of analgesia following the Intrathecal administration of a local anaesthetic is its baricity. The utilisation of 0.5% hyperbaric bupivacaine hydrochloride is widespread due to its extended period of motor and sensory blockage.

. Patients and methods : The impact of Dexmedotomin on spinal anaesthesia.The study focused on individuals who underwent lower limb surgery at Minia University Hospital and received intrathecal Dexmedotomin. During the time frame spanning from February 2022 to September 2023.The patients were divided into two groups: group C, which received a combination of bupivacaine and normal saline (BS) (n = 20), consisting of 3 mL of 0.5% hyperbaric bupivacaine with 0.5 mL of normal saline; and group D, which received a combination of bupivacaine and dexmedetomidine (BD) (n = 20), consisting of 3 mL of 0.5% hyperbaric bupivacaine with dexmedetomidine 10μg. The variables of interest were the time of first analgesic request and the total analgesic requirement, which was ketolac 30mg. Within a span of 24 hours, a record was documented.

Keywords

Main Subjects