(R) Alopecia areata hair pull test and its correlation to histopathological findings.

Articles in Press

Document Type : Original Article

Authors

1 professor and chairperson of Dermatology, STDs and Andrology department Faculty of Medicine, Minia University, Minia, Egypt

2 Professor of Dermatology, STD and Andrology Faculty of Medicine- Minia University-minia- egypt

3 resident of dermatology ,STDS and venereology minia university hospital-minia -Egypt

4 lecturer of dermatology, STDs and venereology minia university hospital-minia -Egypt

5 Associate Professor Western University Pathology and Laboratory Medicine London Health Sciences Centre University Hospital London, Ontario Canada

Abstract

Background: Alopecia areata (AA) is a common non scarring type of hair loss that affects 2% of the general population with unpredictable course. Aim: Histopathological comparing of perifollicular lymphocytic infiltrate in alopecia areata in both longitudinal and transverse sections and its relation to hair pull test. Methods: The study was conducted on 18 AA patients attending the dermatology outpatient clinic, Minia university hospitals from September 2022 to December 2022. Three millimeters punch biopsy was taken from the edge of the lesion in each patient and was processed routinely for longitudinal sections and was stained with hematoxylin and eosin stain then re-embedded and transverse sectioning was performed. Perifollicular mononuclear inflammatory infiltrate was evaluated either significant or not in each case and in each follicle. Result: Significant higher numbers of the terminal hair follicles with significant existence of perifollicular infiltrate were found in transverse sections when compared to longitudinal sections and that immune infiltrates positively correlated to the positive hair pull test.

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Minia Journal of Medical Research

Articles in Press, Accepted Manuscript
Available Online from 03 December 2023

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