Pulmonary arterial hypertension in patients with systemic lupus erythematousus

Document Type : Original Article

Authors

1 cardiology department,faculty of medicicne,Minia university

2 Department of cardiology,minia university,Egypt

3 cardiology department,faculty of medicine ,Minia university

Abstract

Systemic lupus erythematosus (SLE) is a life-threatening multisystem inflammatory condition affecting any organ system

Pulmonary arterial hypertension is severe, potentially life-threatening complication of SLE with range of 1.8% -14%

Aim of the study: to predict of pulmonary arterial hypertension in SLE patients at early stage to prevent further complications

Methods: As a cross-sectional study, 47 patients with systemic lupus erythematosus diagnosed according to EULAR/ACR 2019 criteria were enrolled in Minia university Hospital, cardiology department and rheumatology Clinic. Patients were subjected to full clinical evaluation, laboratory investigations and Echocardiography for detection of pulmonary hypertension

Results: The mean duration of SLE was13.02±6 years. There was a significant relation between severity of SLE disease and pulmonary artery systolic pressure (P < 0.0001). there was no significant difference between 2 groups regarding duration of the disease while pulmonary hypertension was presented in severe form of SLE cases and absent in mild form

Conclusion: There was a significant correlation observed between severity of the SLE disease and pulmonary arterial hypertension

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