R: Detection of drug resistance pattern of Pseudomonas aeruginosa clinical isolates in Minia University hospitals

Document Type : Original Article

Authors

1 Minia ,Eygpt

2 medical microbiology and immunology department, faculty of medicine, minia university

3 Minia ,Egypt

Abstract

Background: Pseudomonas aeruginosa (P. aeruginosa) infection shows a higher morbidity and mortality rates especially in immunosupperessed individuals. It has a high level of resistance through various mechanisms to most antimicrobials. P. aeruginosa can cause severe nosocomial infections, manifesting as pneumonia, surgical site infections, urinary tract infections (UTI) and It is one of the most common causes of bacteremia Methods: From February 2022 to May 2023, 48 samples collected from various infected surgical wound specimens were used in this work. Then, antimicrobial susceptibility tests were done to the isolates by the disc diffusion method .PCR used for detection of gene responsible for antibiotic resistance. Results: Out of 48 samples, 25 isolates were positive for P. aeruginosa and (18/25) 72% were MDR. Conclusion: P. aeruginosa Infections have become a severe problem that requires a precise diagnosis and effective treatment. To replace the current unsuccessful therapies, new alternative treatment plans should be taken into consideration and researched.

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Minia Journal of Medical Research

Articles in Press, Accepted Manuscript
Available Online from 22 August 2023

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