Prognostic Value of Triglyceride Glucose Index in Patients with Type II Diabetes Presented with Acute ST Elevation Myocardial Infarction after Percutaneous Coronary Intervention.

Document Type : Original Article

Authors

1 Department of Cardiology, Faculty of Medicine – Minia University

2 - Department of Clinical Pathology, Faculty of Medicine – Minia University

3 Minia University Faculty of Medicine

Abstract

Abastract

Background: cardiovascular disease pathogenesis is strongly influenced by insulin resistance (IR), the triglyceride-glucose index (TyG index) acts as a rapid and accurate surrogate diagnostic tool of IR diagnosis. Previous data suggests possible prognostic role for TyG index in coronary artery disease patients

Methods:

Patients with diabetes who had STEMI and were treated with primary PCI numbered 175. Patients were divided into two groups based on the presence or absence of major adverse cardiovascular and cerebral events (MACCEs) throughout the follow-up period (30 days, 6 months, and 1 year). The TyG index was determined by taking the logarithm of the ratio of fasting triglycerides to fasting phosphorus.

Results:

More MACCEs and deaths from any cause occurred in patients with STEMI who had higher TyG index values 30 days, 6 months, and 1 year following PCI. Independent of other risk variables, the TyG index was related with a greater incidence of MACCEs in STEMI patients within a year after initial PCI (p = 0.0001).

Conclusion:

Patients with type 2 diabetes with STEMI within 1 year following PCI had an elevated risk of MACCEs, and the TyG index may be used as a strong independent predictor of this increased risk.

Key words:

Insulin resistance (IR), Major adverse cardiac and cerebral events (MACCEs) Triglyceride-glucose index (TyG index), Acute myocardial infarction (AMI), Type 2 diabetes mellitus (T2DM),

Keywords

Main Subjects

Minia Journal of Medical Research

Articles in Press, Accepted Manuscript
Available Online from 17 August 2023

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