the Impact of glycaemic control in Type 2 Diabetes Mellitus patients on left ventricular diastolic function: Two-Dimensional Echocardiography Based Study.

Document Type : Original Article

Authors

1 Cardiology department Faculty of Medicine minia University

2 cardiology department ,faculty of medicine , Mina university., Minia ,Egypt

3 Cardiology department.,Minia University Faculty of Medicine

4 Cardiology department, Faculty of Medicine, Minia University

Abstract

Abstract:



Background: Type 2 Diabetes Mellitus affects left ventricle (LV) diastolic function.

Aim of the study: This study's primary objective was assessment of the LV diastolic Functioning in asymptomatic diabetic individuals with normal blood pressure and comparing it to control group by the use of 2D echocardiography.



Patients and methods: 80 Diabetes Mellitus (DM) type 2 patients were enrolled. We excluded hypertensive patients and Patients with valvular or coronary heart diseases. All patients got thorough clinical and cardiological examination, laboratory work up including (HbA1C, Fasting blood sugar (FBS), post prandial blood sugar (PPS), CBC, Lipid profile, S.Creatinine, albumin and liver enzymes), 12 leads ECG and echocardiographic assessment of both ventricles by tissue Doppler and conventional methods.

Results: In the uncontrolled diabetic individuals, ratio (E/A) of peak early to peak late diastolic flow velocities across mitral were significantly lower than those with controlled diabetes.



Conclusion: Patients with uncontrolled type II DM were associated with compromised left ventricular diastolic function compared to controlled diabetics.

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