Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology

Wagih, Alaa; Abd Elraheem, Sara Mohammed; Abdelgawad, Ehab Ali; Hussein, Nada

doi:10.21608/mjmr.2023.187065.1297

Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology

Document Type : Original Article

Authors

¹ radiology department, faculty of medicine, minia university

² كلية الطب البشرى قسم الأشعة التشخيصية

³ Radiology department, faculty of medicine, Minia University

⁴ Department of clinical oncology

10.21608/mjmr.2023.187065.1297

Abstract

Background: This prospective clinical study is aimed to evaluate the diagnostic value of morphological criteria, the apparent diffusion coefficient (ADC) and diffusion-weighted imaging in differentiating benign from malignant breast lesions in correlation with histopathology.

Method: The study includes 25 females with 25 breast lesions. Routine conventional MRI protocol of the breast was conducted including T2WI, T2 SPAIR and DWI. We used contrast administration in only 10 patients of this study group and DCE-MRI was conducted on them. We compared the conventional unenhanced images to the DCE-MRI by radiologists to detect and characterize breast lesions then we compared the results with the final reference diagnoses supplied by the histopathology. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy for UE-MRI and DCE-MRI were calculated.

Results: The calculated UE-MRI sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 100%, 85.7%, 94.7%, 100%, and 96% respectively. On the other hand, those for the DCE-MRI were 100%, 75%, 85.7%, 100%, and 90% respectively.

Conclusion: The unenhanced MRI of the breast can be an available, reliable, and effective alternative for breast DCE-MRI. Also it can be used with comparable accuracy to DCE-MRI when contrast administration is not suitable or contraindicated.

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