ULTRASOUND AND FLUOROSCOPY GUIDED INTRALESIONAL BLEOMYCIN INJECTION (IBI) FOR TREATMENT OF SUPERFICIAL HEMANGIOMAS AND VASCULAR MALFORMATION.revised

Document Type : Original Article

Authors

1 Radiology department, faculty of medicine, minia university,minia,minia

2 radiology faculty of medicine minia university

3 Vascular Surgery Department

4 Radiology Department, Faculty of Medicine, Minia University, Minia, Egypt

Abstract

Hemangiomas and vascular malformations are benign lesions that can occur at any organ. Currently various medical and surgical options are available for the treatment of hemangiomas including intra lesional bleomycin, laser therapy, cryotherapy, corticosteroids and surgical excision . Recently bleomycin injections is commonly used as a sclerosing agent for the treatment of vascular malformations, compared to the surgery, intra lesional bleomycin injection is a simple, practical non invasive method of treatment. Aim of the work: To evaluate the role of ultrasound and fluoroscopy guided intralesional bleomycin injection (IBI) for treatment of superficial hemangiomas and vascular malformations. This study will be conducted in the interventional radiology unit, department of Radiology, Faculty of Medicine, Minia University. This study is including thirty patients presented with superficial hemangiomas and vascular malformation. There was statistically significant difference in the study regards Relation between response with demographic data, Relation between response and site of lesion, Relation between response with Doppler findings and Relation between response with number of sessions. There was no statistically significant relation between response and size of lesion. Bleomycin appears to be safe, effective and has some antitumor activity and also bleomycin has local sclerosing effect on endothelial cells of hemangiomas and vascular malformation.

Keywords

Main Subjects