Prevalence of cardiovascular calcification in hemodialysis patients and its correlation with serum calcium and phosphorus level

Document Type : Original Article

Authors

1 Department of Internal medicine, El-Minia Faculty of medicine,

2 Department of Clinical Pathology, El-Minia Faculty of medicine, Minia University.

Abstract

Introduction: Compared to the general population, hemodialysis patients are at marked increased risk 
for cardiovascular disease. Vascular calcification, occurring during late-stage vascular and valvular 
disease, is highly associated with chronic kidney disease-mineral and bone disorders (CKD-MBD), 
representing a major risk factor for cardiovascular morbidity and mortality. In CKD, Calcitriol levels 
are reduced and calcium complexes with phosphate, reducing calcium serum levels, causing 
secondary hyperparathyroidism. This leads to phosphate resorption from the bone, paradoxically 
causing a phosphate shift from bone demineralization toward vascular mineralization. Aim of the 
work: The aim of the work is to study Prevalence of cardiovascular calcification in patients in 
hemodialysis unit of Minia university hospital. To evaluate the relationship between cardiovascular 
calcification and serum calcium and phosphorus level. Patients and Methods: Subjects: The current 
study, The study group comprised 80 of hemodialysis patients, 35 males (43.8%) and 45 females 
(56.2%) were selected from hemodialysis unit of Minia university hospital (From august 2018 till 
February 2019). Results: Our study sample is 80 patients, 35 males (43.8%) and 45 females (56.2%)
were selected from hemodialysis unit of Minia university hospital (From august 2018 till February 
2019). Our study Revealed high prevalence of cardio vascular calcification in hemodialysis patients 
and recommend regular follow up and control of serum calcium and phosphorus level in hemodialysis 
patients

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