Relation between serum levels of Vitamin D and Interleukin 6 in type 1 Diabetes in an Egyptian Population

Document Type : Original Article

Authors

1 Department of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt.

2 Department of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt

Abstract

Type 1 diabetes is an inflammatory disease of the pancreatic islets due interaction of activated 
T-cells and proinflammatory cytokines in the immune infiltrate. Vitamin D has vital 
immunomodulatory properties that help in prevention of occurrence of T1DM. IL- 6 is a 
multifunctional cytokine which has role in the pathogeneses of type 1 diabetes. This study 
was conducted to evaluate levels of vitamin D and IL6 in type 1 diabetic children and their 
relation to RBS, glycemic control and c-peptide level.

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