Assessment of fetal adrenal gland volume as prediction of success of labour induction prospective observational study

Document Type : Original Article

Authors

Department of Obstatrics and Gynecology, El-Minia Faculty of Medicine

Abstract

Background/aim: Is to compare the modified Bishop's score, demographic cervical length and fetal 
adrenal gland enlargement in prediction the success of labour induction and duration of labour.
Methodds: This study will be conducted at Minia Maternity hospital as prospective observational 
study. It will include 100 pregnant women with an indication for labour induction. These women will 
be recruited from patients scheduled to under go labour induction at > 37weeks gestation. The most 
common indication for induction will include: postdate pregnancies, Preclampsia, diabetes mellitus 
and intrauterine growth retardation. An informed consent will be obtained from all patients 
participating in this study. Results: fetal gland volume measurement can be achived easily with 
minimal discomfort to patient. Successful induction of labour was more in women with fetal gland 
volume more than 4.8 mm. the best cutovalue for FGV is 4.8mm. Conclusion: More recently another 
study demonstrate that the three dimensional (3D) Ultrasonography measurement of fetal adrenal 
gland volume might help to predict preterm labour.(7) During preterm labour, abnormal activation of 
labour cascade lead to increase production of DHEAS in the central zone of fetal adrenal gland with 
subsequent enlargement of entire fetal adrenal gland.(8) This is first study, which compares the 
modified Bishop's score, Demographic cervical length and fetal adrenal gland enlargement in 
prediction of success of labour induction and duration of labour.
Abbrevation: FGV= FETAL GLAND VOULME, BMI= body mass index, TVUS=trans vaginal 
ultrasound, fz= fetal zone, Tz=transitional zone, CPD= cephalopelvic disproportion.

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