Testicular changes after non fatal electrical injury.

Document Type : Original Article

Authors

Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Minia University, Department of Pathology, Faculty of Medicine, Minia University,

Abstract

Introduction: Electrical injury (EI) can be defined as damage caused by generated electrical current 
passing through the body. Electrical injuries are an emerging health problem in developing countries 
due to the widespread use of electrical appliances with lack of awareness regarding safety issues 
among the general population. Aim of the work: The aim of this study is to detect histopathological 
changes in testes and to evaluate the expression of Caspase-3 in testes of electrically injured rats by 
non-fatal electrical current. Material and Methods: This work was done in forensic medicine and 
clinical toxicology department, faculty of medicine, Minia University. This study included 60 male 
albino rats with average weight 200-250 gm were used. This study was done to detect 
histopathological changes in testes and to evaluate the expression of Caspase 3 in testes of electrically 
injured rats by non-fatal electrical current. All animals were given free access to standard pellet chow 
and water prior to the experiments. All procedures were approved by the Ethical Committee of Minia 
University. Results: there were signicant histopathological changes in testes of the experimental 
animals as well as significant increase in the expression of caspase 3 among experimental groups.
Conclusion: the main pathogenesis of electrical injury on testes was apoptosis and confirmed by 
histipathological changes and elevated caspase 3 level.

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Minia Journal of Medical Research
Volume 31, Issue 1
January 2020
Pages 179-181

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