Differentiation between benign and malignant thyroid nodules by diffusion weighted image and apparent diffusion coefficient

Soliman, Mohammad T. M.; Alam-Aldeen, Mohammad H.; Fotohy, Tarek . E.; Ead, Gehad A. Mohammad

doi:10.21608/mjmr.2022.221490

Differentiation between benign and malignant thyroid nodules by diffusion weighted image and apparent diffusion coefficient

Document Type : Original Article

Authors

¹ Department of Diagnostic Radiology, Faculty of Medicine, Sohag University

² Department of Maxillofasical, Head and Neck Surgery, Faculty of Medicine, Sohag University

10.21608/mjmr.2022.221490

Abstract

Background: There is a great increase in the incidence of thyroid cancer. Thyroid cancer is the most
common endocrine tumor. Magnetic resonance imaging (MRI) has gained importance in the diagnosis
of thyroid cancer. The application of diffusion-weighted MRI (DWI) is an important diagnostic tool
for assessing in vivo tumor characterization. Objective: The purpose of the study is to evaluate the
diagnostic accuracy of diffusion weighted imaging and ADC to differentiate between benign and
malignant thyroid nodules. Methodology: this investigation has been done through assortment of
information from papers which has been looked upon PubMed, the papers have been from 1998 to
2o16, the hunt is finished including just the papers written in English language and assortment of the
information including radiological anatomy of thyroid gland ,hint about the physics of MRI, DWI and
ADC as well as appearance of different thyroid lesions at DWI and ADC. Conclusion: DWI with the
ADC values may be a doable, non-invasive and non-radiative technique for recognizing malignant
from benign thyroid nodules that do not require the administration of contrast media. The b value is a
significant factor, and different b-values must be acquired for more accurate quantitative analysis of
diffusion-weighted images and consequently reliable ADC maps as well as the ADC measurement.

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