Comparison between central venous and arterial gases level versus lactate clearance as an indicator of initial resuscitation in septic patients in intensive care unit
Objective: Aim of this study: was to compare the central venoarterial carbon dioxide difference/arterial-central venous oxygen difference (P(va)CO2/C(a-v)O2) ratio versus lactate clearance as an indicator to evaluate the steps of initial resuscitation in septic patients. Patients and methods: Our study was conducted in the ICU,Minia University Hospital. Eighty patients with severe sepsis or septic shock. Results: There was improvement in CVP, MAP, or Scvo2 at T8 after early resuscitation with no significant differences between group1 and group 2 and inside each group. There were no significant difference in P(v-a)CO2/C(av)O2 ratio at T0 and at T8 at group 1. However there was higher lactate level at T0 and exhibited significantly lower at T8 in group 2. Conclusion: Further clinical trials are needed to conclusively establish lactate clearance as a resuscitation endpoint and an outcome measure to be targeted during the most proximal phases of severe sepsis and septic shock.
Youseif, I., Mohammed, A., & Farghly, R. (2020). Comparison between central venous and arterial gases level versus lactate clearance as an indicator of initial resuscitation in septic patients in intensive care unit. Minia Journal of Medical Research, 31(2), 335-339. doi: 10.21608/mjmr.2022.221095
MLA
Ibrahim A. Youseif; Ahmad H. Mohammed; Rehab M. Farghly. "Comparison between central venous and arterial gases level versus lactate clearance as an indicator of initial resuscitation in septic patients in intensive care unit". Minia Journal of Medical Research, 31, 2, 2020, 335-339. doi: 10.21608/mjmr.2022.221095
HARVARD
Youseif, I., Mohammed, A., Farghly, R. (2020). 'Comparison between central venous and arterial gases level versus lactate clearance as an indicator of initial resuscitation in septic patients in intensive care unit', Minia Journal of Medical Research, 31(2), pp. 335-339. doi: 10.21608/mjmr.2022.221095
VANCOUVER
Youseif, I., Mohammed, A., Farghly, R. Comparison between central venous and arterial gases level versus lactate clearance as an indicator of initial resuscitation in septic patients in intensive care unit. Minia Journal of Medical Research, 2020; 31(2): 335-339. doi: 10.21608/mjmr.2022.221095