Clinical usefulness of serum ferritin level in patients with fatty liver

Document Type : Original Article

Authors

1 Department of Tropical Medicine, Minia University

2 Department of clinical pathology, Minia University.

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic 
liver disease worldwide. Recently several parameters, such as serum ferritin, have emerged as possible 
predictors for the severity of NAFLD and insulin sensitivity. We aimed to investigate the value of serum 
ferritin level as a useful biomarker for the prediction of disease severity in patients with NAFLD.
Methods: This was a prospective cross sectional study in which demographic, clinical and laboratory 
data of 101 adult patients with NAFLD were analyzed. Results: In our patients population with mean age 
of 49.2 years and mean BMI of 31.9, it was also observed that ferritin level did not have a significant 
correlation with the stage of fibrosis (p = 0.835). Conclusion: Hyperferritinemia is common in patients 
with NAFLD but the extent of serum ferritin elevations do not predict the stage of underlying NAFLD 
disease.

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Minia Journal of Medical Research
Volume 31, Issue 2
April 2020
Pages 201-205

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