Evaluation of the Effect of Cell Spray Technique in the Treatment of Partial-thickness Skin Loss.

Document Type : Original Article

Authors

Department of surgery, El-Minia Faculty of Medicine

Abstract

Introduction: Early excision and prompt resurfacing with skin grafts is the mainstay of surgical 
treatment of extensive raw areas. However, early excision with autograft coverage may be difficult to 
be achieved in patients with extensive burns due to the limited size of donor sites. Aim of the work:
The aim of this study is to evaluate the treatment of post-burn and post-traumatic raw areas using Cell 
Spray Technique to better understand its indication at a maximum benefit. Patients and methods: 20 
Patients aged from 2-40 years old with a partial-thickness to deep partial-thickness wound of up to 
20% total body surface area (TBSA) requiring surgical debridement and skin grafting participated in 
this study, underwent cell spray-on grafting on their raw are after harvesting a normal graft from their 
donor site, separate dermis from epidermis, mince the epidermis and put it in a suspension solution of 
ringer Lactate. Results: Majority of patient rejected the sprayed cells or showed subsequent scars that 
scored high on the Vancouver Scar Score. Discussion: We tried to apply the same clinical technique 
of the ReCell device in our study, to best achieve the benefits of minimizing the donor site to cover up 
larger recipient defects in an economic way, by substituting every tool included in the ReCell device 
kit with a cheaper tool from our operating field, trying to maintain the level of quality of the healing 
process and the resultant scar outcome. We tried to assess the quality of healing process and the 
resulting scar, and its relation to every factor we managed in the criteria and to figure out how far 
these elements affected the results of our study. We recommend: Further trials of the technique to 
achieve higher healing quality, and thorough selection of the candidate patients to avoid factors that 
disrupt the healing process and worsen the resultant scar.

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