Effect of High Salt Diet on Bone in Adult Male Albino Rats

Document Type : Original Article

Authors

Department of Physiology, El-Minia Faculty of Medicine

Abstract

high salt diet (HSD) is a dangerous food habit. It has many harmful effects on arterial 
blood pressure, cardiovascular system, and kidney. Aim of work: To assess the effects of the high salt 
diet (HSD) on adult male albino rats' bone. Materials and methods: twenty-four adult male albino 
rats were divided into two groups: Control group and HSD-fed group. Results: Administration of 
HSD (8 %) for seven weeks to male rats resulted in increased food intake, decreased body weight 
gain, and BMI, as well as osteoporosis. There was increase in all bone resorption parameters and 
decrease in bone formation parameters. Conclusion: Accordingly, the results obtained from the 
present study revealed that HSD induced osteoporosis. 
Keywords: Diet, Bone, dangerous food and blood pressur

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