Clinical and two-dimensional radiographic assessment of simvastatin versus mineral trioxide aggregate in pulpotomy of vital immature permanent molars: A12 -month randomized clinical trial.

Shehata, Mohamed Aboalftooh; Elheeny, Ahmad; Yassa, Mina Kamal

doi:10.21608/mjmr.2025.393579.1985

Clinical and two-dimensional radiographic assessment of simvastatin versus mineral trioxide aggregate in pulpotomy of vital immature permanent molars: A12 -month randomized clinical trial.

Articles in Press

Document Type : Original Article

Authors

¹ Pediatric and Community Dentistry Department, Faculty of Dentistry, Minia University

² Paediatric and Community Dentistry Department, Faculty of Dentistry, Minia University, Minia, Egypt.

10.21608/mjmr.2025.393579.1985

Abstract

This randomized controlled study aimed to evaluate the clinical and radiographic success of Simvastatin gel (SMG) versus mineral trioxide aggregate (MTA) in complete pulpotomy of vital immature permanent molars. Methods: Eligible children in the age group of 6 to 8 years with 80 vital immature permanent molars with deep carious lesions were selected. Teeth were randomly assigned into the SMG and MTA groups (40 immature molar per group). After treatment, clinical and radiographic evaluation over 12 months was performed according to the Core Outcome Set (COS) for Vital Pulp Therapy (VPT).

Results: after follow up the Clinical success at 12 months was 90% for SMG and 95% for MTA and the difference wasn’t statistically significant. Radiographic analysis showed that the SMG group had significantly better root elongation. Conclusion: Simvastatin offered comparable clinical and radiographic success to MTA, affirming its potential use in complete pulpotomy of vital immature permanent molars with deep caries.

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