End-tidal carbon dioxide monitoring during procedural sedation: A Controlled Randomized Clinical Study.

Youssef, Ibrahim Abbas; Mohamed, Shimaa Hassan; Lemoun, Marina A. Karam

doi:10.21608/mjmr.2025.370099.1921

End-tidal carbon dioxide monitoring during procedural sedation: A Controlled Randomized Clinical Study.

Articles in Press

Document Type : Original Article

Authors

¹ Anesthesiology & Intensive care department, Faculty of Medicine, El-Minia University, Egypt.

² lecturer in anesthesia and intensive care, Minia university hospital, Minia University

³ Department of Anesthesia and Intensive care, Faculty of medicine, Minia University.

10.21608/mjmr.2025.370099.1921

Abstract

Background: basic anaesthetic procedure performed in the morning is capnography for sedation.

Objectives: assess how varying oxygen flow rates impact end-tidal carbon dioxide monitoring in patients receiving procedural sedation for small gynecological operations.

Subjects: One hundred twenty patients scheduled for minor gynecological operations that required procedural sedation were included in this prospective, randomized, double-blind trial. Three groups of patients were randomly assigned. The oxygen flow rate was 4 L/min for Group A and 6 L/min for Group B. In addition, the oxygen flow rate to Group (C) was 8 L/min. In order to measure EtCO2, capnography was utilized in every group.

Results: End tidal CO2 levels are similar before induction and afterward (P= 0.58). The three groups showed a notable rise in CO2 levels following induction and up until 20 minutes later (P

< 0.001), which was within the normal range of end tidal CO2. After 25 minutes from induction, the three groups' end tidal CO2 levels returned to baseline and remained there until the end of the surgery (p > 0.05), suggesting that the physiological effects of anesthesia were clearly evident. Conversely, there is no statistically significant change over time in the intergroup disparities (p > 0.05).

Conclusion:Patients undergoing small gynecological procedures under deep anesthesia were found to have non-invasive EtCO2 measurements taken by the laryngeal mask airway device independent of oxygen flow rate, according to the study's conclusion. Hypoventilation under sedation can be detected early using non-invasive EtCO2 monitoring.

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