Pyogenic granuloma and its relation to Human Papilloma virus

Articles in Press

Document Type : Original Article

Authors

1 Dermatology, Andrology and STDs department, Faculty of medicine Helwan university

2 Minia University, faculty of Medicine, Department of Dermatology, andrology & STDs. Minia, Egypt

3 Professor of Dermatology, STD's& Andrology Faculty of medicine Minia University

4 Medical biochemistry and Molecular Biology, Faculty of medicine Cairo university

Abstract

Abstract

Introduction: Although many HPVs are harmless and even beneficial members of healthy tissue's microbiota, HR-HPV infection, especially when left untreated for an extended period of time, raises the risk of invasive malignancy. A benign vascular tumor known as a pyogenic granuloma (PG) often develops in the skin and other mucous membranes. [1]

Methods: Participants were twenty patients seen over the course of six months at the Dermatology Outpatient Clinic of Minia University Hospital for vascular acral tumors. The use of consensus primers in polymerase chain reaction (PCR) amplification allowed for the detection of HPV (My09, My11). Amplifying a housekeeping gene at 268 bp ensured that the amplified DNA was intact.

Results: Proliferative HPV particles were detected in just one skin biopsy out of twenty pyogenic granuloma patients.

Conclusion: In this study we found that there is no relation between HPV and PG.

Further studies are suggested to assess the possibility of relation between HPV and other skin tumors.

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Main Subjects

Minia Journal of Medical Research

Articles in Press, Accepted Manuscript
Available Online from 10 November 2024

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