Three Dimensions global radial strain and coronary artery disease severity

Articles in Press

Document Type : Original Article

Authors

1 Professor and Head of Cardiology Department-Faculty of Medicine - Minia University

2 Assistant lecturer of cardiology, Faculty of medicine, South valley university.

3 Cardiology Division, Qena Faculty of medicine, South Valley university

4 cardiology department ,faculty of medicine ,minia university

Abstract

Background: The most prevalent cardiovascular disease is coronary artery disease (CAD). According to the European Society of Cardiology's (ESC) current classification, stable angina pectoris, also known as chronic coronary syndrome, is a common condition that can be disabling. Early-stage coronary artery disease detection may benefit from the use of certain novel noninvasive techniques. In our study, we assessed the relationship between coronary artery disease (CAD) severity and the 3-dimensional global radial strain (GRS) at rest among individuals with stable angina pectoris.

Methods: This Prospective cohort work had been performed on 90 participants aging from 18 to 80 years old, with Stable angina pectoris. Participants had been subdivided into three groups: Group I (n=30): control group with normal coronary angiography and group II (n=60): patients group which subdivided according to Gensini score into two equal subgroups: IIa: simple lesion, low gensini score (Gensini score < 20) and group IIb: complex lesion, high gensini (Gensini score of ≥20).

Results: LV end-diastolic volume , Left ventricular (LV) end-systolic volume, , global radial strain (GRS and LV ejection fraction (LVEF) had been significantly various across the three groups (P <0.0.05). GRS can significantly predict severity of CAD in CCS at cut-off ≤ 32 and 90.0% sensitivity, 73.33% specificity, 62.79% PPV and 93.62% NPV with accuracy of 78.89%.

Conclusions: GRS significantly predict severity of CAD in CCS.

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Minia Journal of Medical Research

Articles in Press, Accepted Manuscript
Available Online from 13 October 2024

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